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Genetic Study |
| Genetic study, consisting of cytogenetic research
and molecular genetic research, is largely carried out by the Department
of Genetics. |
Cytogenetic Research
Individual radiation doses are assessed by evaluation of chromosome
aberration frequency in the blood cells of A-bomb survivors. Radiation
doses can also be estimated with special techniques that measure
trace amounts of radicals that remain in the teeth of A-bomb survivors.
Molecular Genetic Research
By evaluating DNA from parents and children, studies are carried
out to determine whether de novo mutation rates are increased among
the children of A-bomb survivors. Efforts are also being made to
accurately detect radiation-induced mutation rates using mouse models.
Studies have been initiated to examine genomic instability (marked
by high-frequency genome-wide changes) and genetic effects on cancer
(association between radiation exposure and individual genetic characteristics). |
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